11/18/2023 0 Comments Transient global amnesia twice![]() She had a non-contrast computed tomography (CT) scan of the head and non-contrast magnetic resonance imaging (MRI) of the brain, which did not reveal any acute intracranial abnormality. At that time, laboratory workup including ethanol and toxicology screening, erythrocyte sedimentation rate and C-reactive protein were within normal limits. She was notably diagnosed with TGA a few months prior at a hospital in her home state when she had presented with similar symptoms. She denied tobacco, alcohol, or recreational drug use. ![]() Her medical history was remarkable for diabetes mellitus and depression. She denied any focal numbness, weakness, changes in speech or visual disturbances, fevers, chills, lightheadedness, or dizziness. Over time, her confusional state resolved, but she continued to have amnesia with no memory of antecedent events. Given this alteration in her mental status, emergency services were called, and she was brought to the hospital. She appeared to be doing some yard work, in the afternoon, and was subsequently found wandering around in the yard, confused, by her roommate. She remembered putting on make-up and dressing herself earlier that day. On presentation, she was asking repetitive questions about her current location, yet had retained awareness of self (name/profession), and complained of a mild, diffuse headache. She was found to be wandering outside of her home with no memory of antecedent events. This case emphasizes the recognition of TGA as an important neurological diagnosis, uniquely describes not only the recurrence, but the short interval between recurrent episodes.Ī 63-year-old female flight attendant presented to the emergency room with altered mental status and a witnessed episode of confusion lasting 4 h. During the current hospitalization, she remained alert and fully oriented, with resolution of perseveration. ![]() She was notably diagnosed with TGA a few months prior when she had presented with similar symptoms. Brain magnetic resonance imaging revealed scattered foci of increased FLAIR signal within the bilateral periventricular and subcortical white matter. Physical examination and laboratory diagnostics were unremarkable. She had no memory of antecedent events and demonstrated repetitive questioning but retained awareness of self. We report an interesting case of recurrent episodes of TGA in a 63-year-old woman presenting with altered mental status. Transient global amnesia (TGA) is a syndrome characterized by anterograde amnesia with otherwise intact cognitive function, resolving within 24 h of onset, occurring in the absence of neurological changes.
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